Piperine is a standardized extract from the fruits of Piper nigrum L. (black pepper) or Piper longum L and has many benefits like:
- Anti-inflammatory
- Antinociceptive
- Antiarthritic effects
- Bio-Availability Enhancers
Piperine is a standardized extract from the fruits of Piper nigrum L. (black pepper) or Piper longum L. (long pepper). An extract of the active phenolic component, piperine, is well known to provide beneficial physiological effects [6]. It stimulates the digestive enzymes of pancreas, protects against oxidative damage, lowers lipid peroxidation, and enhances the bioavailability of a number of therapeutic drugs. In addition, its anti-inflammatory activities have been demonstrated in rat models of carrageenan-induced rat paw edema, cotton pellet-induced granuloma, and a croton oil-induced granuloma pouch [7]. Constituents of the piper species have shown in vitro inhibitory activity against the enzymes responsible for leukotriene and prostaglandin biosynthesis, 5-lipoxygenase and COX-1, respectively [8]. These effects of piperine seem to be beneficial for inflammatory diseases that are accompanied by severe pain; for example, rheumatoid arthritis.