Mucuna Pruriens Dopamine Support Supplement L Dopa 50% 750 mg 90 Capsules

The plant Mucana Pruriens, also known as “velvet bean,” is a vigorous annual climbing legume plant from mostly cultivated in India and then moved to southeast Asia and Africa. Most parts of Mucana Pruriens has valuable medicinal properties and it has been investigated in various applications, including for its.

1. Anti-diabetic,
2. Aphrodisiac
3. Anti-neoplastic
4. Neuroprotective
5. Anti-epileptic
6. Anti-microbial activities
7. Anti-venom activities have been investigated by Guerranti et al. (2002) and
8. Anti-helminthic activity has been demonstrated by Jalalpure (2007).
9. Demonstrated Analgesic and Anti-inflammatory activity (Hishika et al., 1981).

Q. What is Mucana or velvet bean extract ? What it is used for ?

A. Mucuna pruriens (Fabaceae) is a well-established in Ayurveda sciences and used for the management of male infertility, nervous disorders, and also as an aphrodisiac. It has been clinically shown that its seeds are potentially of substantial medicinal importance. The ancient Indian medical system, Ayurveda, traditionally used Mucana Pruriens, even to treat such things as Parkinson's disease.

Q. How Mucana supports in Anti-Parkinsons ?

A. Mucana Pruriens has been shown to have anti-parkinson and neuroprotective effects, which may be related to its anti-oxidant activity. In addition, anti-oxidant activity of Mucana pruriens has been also demonstrated in vitro by its ability to scavenge DPPH radicals and reactive oxygen species.

Q. What is the main constituents in Mucana ?

Mucana Pruriens is a popular Indian medicinal plant, which has long been used in traditional Ayurvedic Indian medicine, for diseases including parkinsonism. Mucana Pruriens is reported to contain L-dopa as one of its constituents. The beans have also been employed as a powerful aphrodisiac in Ayurveda and have been used to treat nervous disorders and arthritis.

Q. How is the Neuroprotective effect of Mucuna pruriens seeds?

In India, the seeds of M. pruriens have traditionally been used as a nervine tonic, and as an aphrodisiac for male virility. The pods are anthelmintic, and the seeds are anti-inflammatory. Powdered seeds possess anti-parkinsonism properties, possibly due to the presence of L-dopa (a precursor of neurotransmitter dopamine). It is well known that dopamine is a neurotransmitter. The dopamine content in brain tissue is reduced when the conversion of tyrosine to L-dopa is blocked. L-Dopa, the precursor of dopamine, can cross the blood-brain barrier and undergo conversion to dopamine, restoring neurotransmission (Kulhalli, 1999).

Q. How does Mucana supports Anti-diabetic effect?

According to Anktar et al., (1990), M. pruriens seeds used at a dose of 500 mg/kg reduced plasma glucose levels. These and other data demonstrated that the amount of seeds necessary to obtain a significant anti-diabetic effect contain a total of approximately 7 mg of d-chiro-inositol (including both free, and that derived from the hydrolysis of FP1 and FP2). The anti-diabetic properties of M. pruriens seed EtOH/H2O 1:1 extract are most likely due to d-chiro-inositol and its galacto-derivatives.

Q. Does Mucuna Pruriens supports Anti-oxidant functions?

A. Mucana Pruriens seeds and the whole plant contains large amounts of phenolic compounds, exhibits high anti-oxidant and free radical scavenging activities. These in vitro assays indicate that this plant extract is a significant source of natural anti-oxidant, which may be useful in preventing various oxidative stresses. It has been reported that methanolic extracts of Mucana Pruriens leaves have numerous biochemical and physiological activities, and contain pharmaceutically valuable compounds.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942911/

1. Akhtar M.S, Qureshi A.Q, Iqbal J. Antidiabetic evaluation of Mucuna pruriens Linn seeds. JPMA. 1990;40:147–150.
2. Amin K.M.Y, Khan M.N, Zillur-Rehman S, Khan N.A. Sexual function improving effect of Mucuna pruriens in sexually normal male rats. Fitoterapia Milano. 1996;67:53–56.
3. Awang D, Buckles D, Arnason J.T. Chapeco, Catarina, Brazil, Santa Catarina, Brazil: Paper presented at the International Workshop on Green Manure – Cover Crop Systems for Smallholders in Tropical and Subtropical Regions 6-12 Apr, Rural Extension and Agricultural Research Institute of Santa Catarina; 1997. The phytochemistry, toxicology and processing potential of the covercrop velvetbean (cow(h)age, cowitch) (Mucuna Adans. spp, Fabaceae)
4. Bailey L.H, Bailey Z.E. New York, NY, USA: Macmillan; 1976. Hortus third: a concise dictionary of plants cultivated in the United States and Canada.
5. Beta T, Nam S, Dexter J.E, Sapirstein H.D. Phenolic content and antioxidant activity of pearled wheat and roller-milled fractions. Cereal Chem. 2005;82:390–393.
6. Bravo L, Siddhuraju P, Saura-Calixto F. Effect of various processing methods on the in vitrostarch digestibility and resistant starch content of Indian pulses. J. Agric. Food. Chem. 1998;46:4667–4674.
7. Briganti S, Picardo M. Antioxidant activity, lipid peroxidation and skin diseases What's new. J Eur Acad Dermatol Venereol. 2003;17:663–9.
8. Chaudhri R.D. Herbal drug industry: a practical approach to industrial pharmacognosy. 1996
9. Di Patrizi L, Rosati F, Guerranti R, Pagani R, Gerwig G.J, Kamerling J.P. Structural characterization of the N-glycans of gpMuc from Mucuna pruriens seeds. 2006 10. D’Mello J.P.F. Anti-nutritional substances in legume seeds. In: D’Mello J.P.F, Devendra C, editors. Tropical Legumes in Animal Nutrition, CAB INTERNATIONAL. Wallingford, U.K: 1995. pp. 135–172.